منابع مشابه
3D-QSAR and Molecular Docking Studies on the TcPMCA1-Mediated Detoxification of Scopoletin and Coumarin Derivatives
The carmine spider mite, Tetranychus cinnabarinus (Boisduval), is an economically important agricultural pest that is difficult to prevent and control. Scopoletin is a botanical coumarin derivative that targets Ca2+-ATPase to exert a strong acaricidal effect on carmine spider mites. In this study, the full-length cDNA sequence of a plasma membrane Ca2+-ATPase 1 gene (TcPMCA1) was cloned. The se...
متن کاملStudies on digitalis. XVI. Effects on myocardial oxygen consumption.
The effects of cardiac glycosides on myocardial oxygen consumption (MVo2) have been investigated extensively, and although the results of these studies have not been entirely uniform, it is now generally considered that these agents are "the only drugs which increase the force of contraction of the myocardium without at the same time increasing oxygen consumption" (1). The finding in previous i...
متن کاملThe Antioxidant Activity of New Coumarin Derivatives
The antioxidant activity of two synthesized coumarins namely, N-(4,7-dioxo-2- phenyl-1,3-oxazepin-3(2H,4H,7H)-yl)-2-(2-oxo-2H-chromen-4-yloxy)acetamide 5 and N-(4-oxo-2-phenylthiazolidin-3-yl)-2-(2-oxo-2H-chromen-4-yloxy)acetamide 6 were studied with the DPPH, hydrogen peroxide and nitric oxide radical methods and compared with the known antioxidant ascorbic acid. Compounds 5 and 6 were synthes...
متن کاملStudies on Digitalis . XVI . Effects on Myocardial Oxygen Consumption
The effects of cardiac glycosides on myocardial oxygen consumption (MVo2) have been investigated extensively, and although the results of these studies have not been entirely uniform, it is now generally considered that these agents are "the only drugs which increase the force of contraction of the myocardium without at the same time increasing oxygen consumption" (1). The finding in previous i...
متن کامل[New coumarin derivatives with expected biological activity].
A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation. Some representative compounds showed antitumor activity in vitro on Ehrlich ascites carcinoma in the preliminary testing.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1957
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.77.5_544